NBC's Chuck Todd: Mr. President, could you update us on your latest thinking of where you think things are in Syria, and in particular, whether you envision using U.S. military, if simply for nothing else, the safe keeping of the chemical weapons, and if you're confident that the chemical weapons are safe?

President Obama: On Syria, obviously this is a very tough issue. I have indicated repeatedly that President al-Assad has lost legitimacy, that he needs to step down. So far, he hasn’t gotten the message, and instead has double downed in violence on his own people. The international community has sent a clear message that rather than drag his country into civil war he should move in the direction of a political transition. But at this point, the likelihood of a soft landing seems pretty distant.

What we’ve said is, number one, we want to make sure we’re providing humanitarian assistance, and we’ve done that to the tune of $82 million, I believe, so far. And we’ll probably end up doing a little more because we want to make sure that the hundreds of thousands of refugees that are fleeing the mayhem, that they don’t end up creating -- or being in a terrible situation, or also destabilizing some of Syria’s neighbors.

The second thing we’ve done is we said that we would provide, in consultation with the international community, some assistance to the opposition in thinking about how would a political transition take place, and what are the principles that should be upheld in terms of looking out for minority rights and human rights. And that consultation is taking place.

I have, at this point, not ordered military engagement in the situation. But the point that you made about chemical and biological weapons is critical. That’s an issue that doesn’t just concern Syria; it concerns our close allies in the region, including Israel. It concerns us. We cannot have a situation where chemical or biological weapons are falling into the hands of the wrong people.

We have been very clear to the Assad regime, but also to other players on the ground, that a red line for us is we start seeing a whole bunch of chemical weapons moving around or being utilized. That would change my calculus. That would change my equation.

Todd: So you're confident it’s somehow under -- it's safe?

Obama: In a situation this volatile, I wouldn’t say that I am absolutely confident. What I’m saying is we’re monitoring that situation very carefully. We have put together a range of contingency plans. We have communicated in no uncertain terms with every player in the region that that’s a red line for us and that there would be enormous consequences if we start seeing movement on the chemical weapons front or the use of chemical weapons. That would change my calculations significantly.